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Development and immunogenicity evaluation of a quadruple-gene-deleted pseudorabies virus strain

20 Sept 2024

Abstract excerpt

Since 2011, the emergence of Pseudorabies virus (PRV) variants has led to significant vaccine failures, resulting in severe economic losses in China’s swine industry. Conventional PRV vaccines have shown limited efficacy against these emergent variants, underscoring the urgent need for novel immunization strategies. This study aimed to develop and evaluate a novel recombinant PRV vaccine candidate with improved...

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PMID: 39372271
DOI: 10.3389/fmicb.2024.1479794

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