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Article

Association of genetic ancestry with pre-eclampsia in multi-ethnic cohorts of pregnant women.

Pregnancy hypertension - 1 Dec 2024

Conti-Ramsden Frances, de Marvao Antonio, Gill Carolyn, Chappell Lucy C, Myers Jenny, Vuckovic Dragana, Dehghan Abbas, Hysi Pirro G

Abstract excerpt

OBJECTIVES: Maternal self-reported ethnicity is recognised as a risk factor for pre-eclampsia in clinical screening tools and models. This study investigated whether ethnicity is acting as a proxy for genetic variants in this context. STUDY DESIGN: A total of 436 women from multi-ethnic backgrounds recruited to two UK observational pregnancy hypertension cohort studies were genotyped. Genetically-computed...

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PMID: 39368288
DOI: 10.1016/j.preghy.2024.101162

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