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Value of Pharmacogenetic Testing Assessed with Real-World Drug Utilization and Genotype Data.

Clinical pharmacology and therapeutics - 1 Jan 2025

Litonius Kaisa, Kulla Noora, Falkenbach Petra, Kristiansson Kati, Tarkiainen E Katriina, Ukkola-Vuoti Liisa, Cajanus Kristiina, Korhonen Mari, Khan Sofia, Sistonen Johanna, Orpana Arto, Lindstedt Mats, Nyrönen Tommi, Perola Markus, Turpeinen Miia, Kytö Ville, Tornio Aleksi, Niemi Mikko

Abstract excerpt

Implementation of pharmacogenetic testing in clinical care has been slow and with few exceptions is hindered by the lack of real-world evidence on how to best target testing. In this retrospective register-based study, we analyzed a nationwide cohort of 1,425,000 patients discharged from internal medicine or surgical wards and a cohort of 2,178 university hospital patients for purchases and prescriptions of...

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PMID: 39365028
DOI: 10.1002/cpt.3458
PMCID: PMC11652815

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