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Tyzzerella nexilis strains enriched in mobile genetic elements are involved in progressive multiple sclerosis

27 Sept 2024

Abstract excerpt

Multiple sclerosis (MS) is an autoimmune-demyelinating disease with an inflammatory pathology formed by self-reactive lymphocytes with activated glial cells. Progressive MS, characterized by resistance to medications, significantly differs from the non-progressive form in gut microbiome profiles. After confirming an increased abundance of "Tyzzerella nexilis" in various cohorts of progressive MS, we identified a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39341204
DOI: 10.1016/j.celrep.2024.114785

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