Blind Brush Biopsy: Quantification of Epstein–Barr Virus and Its Host DNA Methylation in the Detection of Nasopharyngeal Carcinoma

Abstract excerpt

Background: The nasopharyngeal brush sampling can effectively collect samples from the nasopharynx. The blind brush sampling does not require the guidance of endoscopy, which is favorable for implementation and dissemination in the community. This study explored methylation markers for nasopharyngeal carcinoma (NPC) at both Epstein–Barr virus (EBV) and its host genome levels, aiming to construct a blind brushing...

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