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Replacing sperm with genotyped haploid androgenetic blastomeres to generate cattle with predetermined paternal genomes†.

Biology of reproduction - 12 Dec 2024

Aguila Luis, Sampaio Rafael V, Therrien Jacinthe, Nociti Ricardo P, Labrecque Remi, Tremblay Amelie, Marras Gabrielle, Blondin Patrick, Smith Lawrence C

Abstract excerpt

Although meiosis plays an essential role for the survival of species in natural selection, the genetic diversity resulting from sexual reproduction impedes human-driven strategies to transmit the most suitable genomes for genetic improvement, forcing breeders to select diploid genomes generated after fertilization, that is, after the encounter of sperm and oocytes carrying unknown genomes. To determine whether...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 39303105
DOI: 10.1093/biolre/ioae135

Genes

IGF2
IGF2R
KCNQ1
PHLDA2
SNRPN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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