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The lysogenic filamentous Pseudomonas bacteriophage phage Pf slows mucociliary transport

1 Sept 2024

Abstract excerpt

Abstract Pseudomonas aeruginosa is a major pulmonary pathogen causing chronic pulmonary infections in people with cystic fibrosis (CF). The P. aeruginosa filamentous and lysogenic bacteriophage, Pf phage, is abundant in the airways of many people with CF and has been associated with poor outcomes in a cross-sectional cohort study. Previous studies have identified roles for Pf phage in biofilm formation,...

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PMID: 39301510
DOI: 10.1093/pnasnexus/pgae390

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