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A genome assembly and transcriptome atlas of the inbred Babraham pig to illuminate porcine immunogenetic variation.

Immunogenetics - 1 Dec 2024

Schwartz John C, Farrell Colin P, Freimanis Graham, Sewell Andrew K, Phillips John D, Hammond John A

Abstract excerpt

The inbred Babraham pig serves as a valuable biomedical model for research due to its high level of homozygosity, including in the major histocompatibility complex (MHC) loci and likely other important immune-related gene complexes, which are generally highly diverse in outbred populations. As the ability to control for this diversity using inbred organisms is of great utility, we sought to improve this resource...

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PMID: 39294478
DOI: 10.1007/s00251-024-01355-7
PMCID: PMC11496355

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