Article
Effects of periodic bottlenecks on the dynamics of adaptive evolution in microbial populations.
Microbiology (Reading, England) - 1 Sept 2024
Izutsu Minako, Lake Devin M, Matson Zachary W D, Dodson Jack P, Lenski Richard E
Abstract excerpt
Population bottlenecks can impact the rate of adaptation in evolving populations. On the one hand, each bottleneck reduces the genetic variation that fuels adaptation. On the other hand, each founder that survives a bottleneck can undergo more generations and leave more descendants in a resource-limited environment, which allows surviving beneficial mutations to spread more quickly. A theoretical model predicted...
Topics
- Escherichia coli
- Mutation
- Adaptation, Physiological
- Genetic Fitness
- Selection, Genetic
- Biological Evolution
- Evolution, Molecular
- Genetic Variation
- Computer Simulation