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Article

Manipulation of natural transformation by AbaR-type islands promotes fixation of antibiotic resistance in Acinetobacter baumannii.

Proceedings of the National Academy of Sciences of the United States of America - 24 Sept 2024

Tuffet Rémi, Carvalho Gabriel, Godeux Anne-Sophie, Mazzamurro Fanny, Rocha Eduardo P C, Laaberki Maria-Halima, Venner Samuel, Charpentier Xavier

Abstract excerpt

The opportunistic pathogen Acinetobacter baumannii, carries variants of A. baumannii resistance islands (AbaR)-type genomic islands conferring multidrug resistance. Their pervasiveness in the species has remained enigmatic. The dissemination of AbaRs is intricately linked to their horizontal transfer via natural transformation, a process through which bacteria can import and recombine exogenous DNA, effecting...

Topics

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Acinetobacter baumannii
Anti-Bacterial Agents
Bacterial Proteins
Drug Resistance, Multiple, Bacterial

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gene Transfer, Horizontal

Genomic Islands

Polymorphism, Single Nucleotide

Transformation, Bacterial

Source

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Identifiers

PMID: 39288183
DOI: 10.1073/pnas.2409843121
PMCID: PMC11441513

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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