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Article

Regional and temporal genotype profiling of Clostridioides difficile in a multi-institutional study in Japan.

Scientific reports - 16 Sept 2024

Sagisaka Yusaku, Ishibashi Miyako, Hosokawa Daisuke, Nakagawa Hikaru, Yonogi Shinya, Minami Kenta, Suzuki Youichi, Ogawa Taku, Ukimura Akira, Nakano Takashi, Komano Jun

Abstract excerpt

Clostridioides difficile, a cause of healthcare-associated infections, poses a significant global health threat. This multi-institutional retrospective study focuses on epidemic dynamics, emphasizing minor and toxin-negative clinical isolates through high-resolution genotyping. The genotype of the C. difficile clinical isolates during 2005 to 2022 was gathered from 14 hospitals across Japan (N = 982). The total...

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PMID: 39284883
DOI: 10.1038/s41598-024-72252-y
PMCID: PMC11405520

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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