Article
Analysis of randomly mutated AlSRKb genes reveals that most loss-of-function mutations cause defects in plasma membrane localization.
The New phytologist - 1 Nov 2024
Yamamoto Masaya, Ohtake Shotaro, Shinozawa Akihisa, Shirota Matsuyuki, Mitsui Yuki, Kitashiba Hiroyasu
Abstract excerpt
Only very limited information is available on why some nonsynonymous variants severely alter gene function while others have no effect. To identify the characteristic features of mutations that strongly influence gene function, this study focused on SRK which encodes a highly polymorphic receptor kinase expressed in stigma papillary cells that underlies a female determinant of self-incompatibility in...
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