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Article

Neutrophil phenotype, effector functions, and microbicidal activity in patients with SARS-CoV-2-associated ARDS.

Journal of leukocyte biology - 31 Dec 2024

Quelven Quentin, Grégoire Murielle, Coirier Valentin, Gacouin Arnaud, Le Gallou Simon, Cattoir Vincent, Cogné Michel, Guegan Hélène, Gangneux Jean-Pierre, Roussel Mikael, Tarte Karin, Tadié Jean-Marc, Lesouhaitier Mathieu

Abstract excerpt

Critically ill patients admitted to the intensive care unit (ICU) for SARS-CoV-2-induced acute respiratory distress syndrome (ARDS) are at increased risk of bacterial and fungal secondary pulmonary infections due to acquired immune dysfunction. Given that the activity of neutrophils has not been described in these patients, we aimed to investigate the function of neutrophils at ICU admission and on day 7 (D7)...

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Identifiers

PMID: 39268804
DOI: 10.1093/jleuko/qiae195

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