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Article

Causal association between B cell count and psoriasis using two-sample Mendelian randomization.

Journal of cellular and molecular medicine - 1 Sept 2024

Zhao Zongfeng, Cheng Jie, Zhu Jian, Lu Sheng, Lv Hongli, Wu Xiujuan

Abstract excerpt

To investigate the causality between B cell count and psoriasis by Mendelian randomization (MR). Collected B cell count and psoriasis data from IEU Open GWAS Project. Employed inverse variance weighting (IVW), MR-Egger, WM, weighted mode for analysis, ensuring result robustness. Assessed horizontal pleiotropy with MR-Egger, detected outliers using MR-PRESSO and examined instrumental variables heterogeneity with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39261978
DOI: 10.1111/jcmm.70089
PMCID: PMC11390492

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