Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic spectrum features and diagnostic accuracy of four plasma biomarkers in 248 Chinese patients with frontotemporal dementia.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Oct 2024

Xu Tianyan, Weng Ling, Zhang Cong, Xiao Xuewen, Yang Qijie, Zhu Yuan, Zhou Yafang, Liao Xinxin, Luo Shilin, Wang Junling, Tang Beisha, Jiao Bin, Shen Lu

Abstract excerpt

INTRODUCTION: Frontotemporal dementia (FTD) is characterized by phenotypic and genetic heterogeneities. However, reports on the large Chinese FTD cohort are lacking. METHODS: Two hundred forty-eight patients with FTD were enrolled. All patients and 2010 healthy controls underwent next generation sequencing. Plasma samples were analyzed for glial fibrillary acidic protein (GFAP), α-synuclein (α-syn), neurofilament...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Synuclein
Share to Biomarkers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to C9orf72 Protein

Share to East Asian People

Share to Frontotemporal Dementia

Share to Glial Fibrillary Acidic Protein

Share to Neurofilament Proteins

Share to tau Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 39254359
DOI: 10.1002/alz.14215
PMCID: PMC11485083

Genes

GFAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic spectrum features and diagnostic accuracy of four plasma biomarkers in 248 Chinese patients with frontotemporal dementia.PMID 39254359Read ↗

C9orf72 expansions are the most common cause of genetic frontotemporal dementia in a Southeast Asian cohort.Semantic proximity Read ↗

Precision medicine of frontotemporal dementia: from genotype to phenotype.Semantic proximity Read ↗

A genetic and proteomic comparison of key AD biomarkers across tissuesSemantic proximity Read ↗

Identification and functional characterization of novel variants of MAPT and GRN in Chinese patients with frontotemporal dementia.Semantic proximity Read ↗

Clinico-genetic findings in 509 frontotemporal dementia patients.Semantic proximity Read ↗

The role of genetics in neurodegenerative dementia: a large cohort study in South ChinaSemantic proximity Read ↗

Underlying genetic variation in familial frontotemporal dementia: sequencing of 198 patients.Semantic proximity Read ↗

Plasma GFAP, NfL, and p-tau181 levels as early biomarkers of dementia in Chinese adults: Shenzhen community cohort studySemantic proximity Read ↗

An update on genetic frontotemporal dementiaSemantic proximity Read ↗

Genetic Spectrum and Clinical Heterogeneity of Chinese Frontotemporal Dementia Patients: Data from PUMCH Dementia Cohort.Semantic proximity Read ↗

Proteomic analysis reveals distinct cerebrospinal fluid signatures across genetic frontotemporal dementia subtypesSemantic proximity Read ↗

Plasma biomarkers and genetics in the diagnosis and prediction of Alzheimer’s diseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.