Article
Deciphering the causal association and underlying transcriptional mechanisms between telomere length and abdominal aortic aneurysm.
Frontiers in immunology - 1 Jan 2024
Zhang Jiyu, Xia Xinyi, He Shujie
Abstract excerpt
Background: The purpose of this study is to investigate the causal effect and potential mechanisms between telomere length and abdominal aortic aneurysm (AAA). Methods: Summary statistics of telomere length and AAA were derived from IEU open genome-wide association studies and FinnGen R9, respectively. Bi-directional Mendelian randomization (MR) analysis was conducted to reveal the causal relationship between AAA...
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