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Metagenomics Analysis Reveals Unique Gut Microbiota Signature of Slow-Transit Constipation

3 Sept 2024

Abstract excerpt

INTRODUCTION: Altered gut microbiota may play a role in slow-transit constipation (STC). We conducted a study of gut microbiota composition and functionality in STC using metagenomic analyses. METHODS: We assembled a clinical cohort of 24 patients with STC physiology age- and sex-matched to 24 controls. We performed shotgun metagenomic sequencing followed by prediction of metabolite composition from functional...

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PMID: 39225513
DOI: 10.14309/ctg.0000000000000766

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