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Bottom‐Up Design of Prebiotics and Probiotics: An Intestinal Microbiota‐Centered Approach to Chronic and Functional Constipation Management

17 Jun 2025

Abstract excerpt

Chronic constipation (CC) and functional constipation (FC) are common gastrointestinal disorders that significantly affect quality of life. This study investigates the intestinal microbiota characteristics in CC and FC patients, revealing microbial imbalances characterized by reduced beneficial taxa, such as Acinetobacter, Blautia, Dorea formicigenerans, Eubacterium ramulus, and Halomonas, alongside increased...

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PMID: 40528675
DOI: 10.1002/mnfr.70140

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