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Article

Single-cell analyses of polyclonal Plasmodium vivax infections and their consequences on parasite transmission.

Nature communications - 2 Sept 2024

Hazzard Brittany, Sá Juliana M, Bogale Haikel N, Pascini Tales V, Ellis Angela C, Amin Shuchi, Armistead Jennifer S, Adams John H, Wellems Thomas E, Serre David

Abstract excerpt

Most Plasmodium vivax infections contain genetically distinct parasites, but the consequences of this polyclonality on the development of asexual parasites, their sexual differentiation, and their transmission remain unknown. We describe infections of Saimiri monkeys with two strains of P. vivax and the analyses of 80,024 parasites characterized by single cell RNA sequencing and individually genotyped. In our...

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Identifiers

PMID: 39223117
DOI: 10.1038/s41467-024-51949-8
PMCID: PMC11369214

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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