Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The effect of genetic polymorphisms in STIM1 and ORAI1 on erythropoietin resistance in Egyptian patients with end-stage renal disease.

Clinica chimica acta; international journal of clinical chemistry - 1 Jan 2025

Gomaa Azza A E, Zeid Amany M A, Nagy Ibrahim M, Zahran Ahmed M

Abstract excerpt

Chronic renal failure (CRF) is an incurable disease with unique challenges. Anemia is a frequent complication affecting dialysis patients. Erythropoietin (EPO) is used to treat anemia, but a poor response may result. We investigated genetic polymorphisms of store-operated calcium channel (SOC) signaling, an important erythropoietin-activated pathway that may induce EPO resistance in patients with renal failure. A...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance
Share to Egypt

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Erythropoietin

Share to Kidney Failure, Chronic

Share to Neoplasm Proteins

Share to ORAI1 Protein

Share to Polymorphism, Single Nucleotide

Share to Stromal Interaction Molecule 1

Source

Identifiers

PMID: 39214396
DOI: 10.1016/j.cca.2024.119948

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The effect of genetic polymorphisms in STIM1 and ORAI1 on erythropoietin resistance in Egyptian patients with end-stage renal disease.PMID 39214396Read ↗

Precision Medicine in Erythropoietin Deficiency and Treatment Resistance: A Novel Approach in management of Anemia of Chronic Kidney DiseaseSemantic proximity Read ↗

Role of ACE and IL-1β Gene Polymorphisms in Erythropoeitin Hyporesponsive Patients with Chronic Kidney Disease with Anemia.Semantic proximity Read ↗

Genetic polymorphisms of stromal interaction molecule 1 associated with the erythrocyte sedimentation rate and C-reactive protein in HLA-B27 positive ankylosing spondylitis patients.Semantic proximity Read ↗

<i>STIM1</i> Mutation Associated with a Syndrome of Immunodeficiency and AutoimmunitySemantic proximity Read ↗

A case-control study between the STIM1 gene and hypertensive disorders of pregnancy.Semantic proximity Read ↗

Evaluation for the Genetic Association between Store-Operated Calcium Influx Pathway (STIM1 and ORAI1) and Human Hepatocellular Carcinoma in Patients with Chronic Hepatitis B InfectionSemantic proximity Read ↗

Single nucleotide polymorphisms in the non-coding region of STIM1 gene are associated with Parkinson disease risk in Chinese Han population.Semantic proximity Read ↗

Erythropoietin single nucleotide polymorphisms are associated with anemia and dyslipidemia in a cardiovascular disease populationSemantic proximity Read ↗

Stim1 Polymorphism Disrupts Immune Signaling and Creates Renal Injury in Hypertension.Semantic proximity Read ↗

Real World Use of Pegylated Erythropoietin in CKD Anemia: An Indian Modified Delphi ConsensusSemantic proximity Read ↗

Store-operated calcium entry dysfunction in CRAC channelopathy: Insights from a novel STIM1 mutation.Semantic proximity Read ↗

Modulation of STIM1 by a risk insertion/deletion polymorphism underlying genetics susceptibility to sudden cardiac death originated from coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.