Article
Distinct clinical trajectories of gastrointestinal progression among patients with systemic sclerosis.
Rheumatology (Oxford, England) - 1 May 2025
Perin Jamie, Hughes Michael, Mecoli Christopher A, Paik Julie J, Gelber Allan C, Wigley Fredrick M, Hummers Laura K, Shah Ami A, Zeger Scott L, McMahan Zsuzsanna H
Abstract excerpt
OBJECTIVES: Systemic sclerosis (SSc) is heterogeneous in its clinical presentation. Common manifestations cluster together, defining unique subgroups. This investigation aims to characterize gastrointestinal (GI) phenotypes and determine whether they can be distinguished by temporal progression. METHODS: We examined a well-established SSc patient cohort with a modified Medsger GI severity score measured over time...
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