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Maternal immune cell gene expression associates with maternal gut microbiome, milk composition and infant gut microbiome

30 Aug 2024

Abstract excerpt

BACKGROUND: Pre-pregnancy overweight and obesity promote deleterious health impacts on both mothers during pregnancy and the offspring. Significant changes in the maternal peripheral blood mononuclear cells (PBMCs) gene expression due to obesity are well-known. However, the impact of pre-pregnancy overweight on immune cell gene expression during pregnancy and its association with maternal and infant outcomes is...

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PMID: 39209027
DOI: 10.1016/j.clnesp.2024.08.027

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