Pediatric Cancer Screening in Hereditary Gastrointestinal Cancer Risk Syndromes: An Update from the AACR Childhood Cancer Predisposition Working Group.

doi:10.1158/1078-0432.CCR-24-0953

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Pediatric Cancer Screening in Hereditary Gastrointestinal Cancer Risk Syndromes: An Update from the AACR Childhood Cancer Predisposition Working Group.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2024

MacFarland Suzanne P, Becktell Kerri, Schneider Kami Wolfe, Kuiper Roland P, Lesmana Harry, Meade Julia, Nichols Kim E, Porter Christopher C, Savage Sharon A, Schultz Kris Ann, Scott Hamish, States Lisa, Tabori Uri, Tamura Chieko, Tomlinson Gail, Zelley Kristin, Durno Carol, Bauer Andrew, Plon Sharon E

Abstract excerpt

Gastrointestinal (GI) polyposis and cancer in pediatric patients is frequently due to an underlying hereditary cancer risk syndrome requiring ongoing cancer screening. Identification of at-risk patients through family history, clinical features of a syndrome, or symptom onset ensures appropriate cancer risk assessment and management in childhood and beyond. In this 2024 perspective, we outline updates to the...

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PMID: 39190470
DOI: 10.1158/1078-0432.CCR-24-0953

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