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A group B streptococcal type VII-secreted LXG toxin mediates interbacterial competition and colonization of the murine female genital tract

27 Aug 2024

Abstract excerpt

ABSTRACT Group B Streptococcus (GBS) asymptomatically colonizes the vagina but can opportunistically ascend to the uterus and be transmitted vertically during pregnancy, resulting in neonatal pneumonia, bacteremia, and meningitis. GBS is a leading etiologic agent of neonatal infection and understanding the mechanisms by which GBS persists within the polymicrobial female genital mucosa has the potential to...

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PMID: 39189749
DOI: 10.1128/mbio.02088-24

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