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Article

Associations Between Gut Microbiota and Alcohol Abuse: A Mendelian Randomisation and Bioinformatics Study.

Journal of molecular neuroscience : MN - 26 Aug 2024

Wang Xu, Pan Lei, Gu Jingyan, Gu Lianping, Lou Meiqing, Liu Yaohua

Abstract excerpt

Alcohol abuse, also known as Alcohol Use Disorder (AUD), is a substance dependency psychiatric disorder. We aimed to establish a causal relationship between specific gut microbiota and alcohol abuse using Mendelian Randomisation (MR) and bioinformatics methods. We acquired summary data of genome-wide association studies (GWAS) for gut microbiota and alcohol abuse from the Mibiogen and Finngen databases,...

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PMID: 39186136
DOI: 10.1007/s12031-024-02259-7

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