Biomarker defined infective and inflammatory asthma exacerbation phenotypes in hospitalized adults: clinical impact and phenotype stability at recurrent exacerbation.

Abstract excerpt

OBJECTIVE: Acute exacerbations (AEs) of asthma are heterogeneous in terms of triggers, outcomes, and treatment response. This study investigated biomarker defined infective and inflammatory AE phenotypes in hospitalized adult asthma patients, and their impact on clinical outcomes and phenotype stability at AE recurrence. METHOD: Patients with asthma admitted with an AE between January 2010 and December 2011 with...

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• Asthma
• Bacterial Infections
• C-Reactive Protein
• Disease Progression