Article
The Causal Effect of Intrapancreatic Fat Deposition on Acute and Chronic Pancreatitis: A Mendelian Randomization Study.
The American journal of gastroenterology - 1 Dec 2024
Yamazaki Hajime, Heni Martin, Wagner Róbert, Fukuhara Shunichi, Grossman Steven R, Han Sihao, Wu Lang, Streicher Samantha A, Huang Brian Z
Abstract excerpt
INTRODUCTION: Recent associative studies have linked intrapancreatic fat deposition (IPFD) with risk of pancreatitis, but the causal relationship remains unclear. METHODS: Using Mendelian randomization, we evaluated the causal association between genetically predicted IPFD and pancreatitis. This approach used genetic variants from genomewide association studies of IPFD (n = 25,617), acute pancreatitis (n = 6,787...
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