Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clinical application of whole genome sequencing in young onset dementia: challenges and opportunities.

Expert review of molecular diagnostics - 1 Aug 2024

Huq Aamira, Thompson Bryony, Winship Ingrid

Abstract excerpt

INTRODUCTION: Young onset dementia (YOD) by its nature is difficult to diagnose. Despite involvement of multidisciplinary neurogenetics services, patients with YOD and their families face significant diagnostic delays. Genetic testing for people with YOD currently involves a staggered, iterative approach. There is currently no optimal single genetic investigation that simultaneously identifies the different...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Dementia
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Testing

Share to Polymorphism, Single Nucleotide

Share to Whole Genome Sequencing

Source

Identifiers

PMID: 39135326
DOI: 10.1080/14737159.2024.2388765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clinical application of whole genome sequencing in young onset dementia: challenges and opportunities.PMID 39135326Read ↗

Clinical impact of whole-genome sequencing in patients with early-onset dementiaSemantic proximity Read ↗

Genetic testing in dementia - utility and clinical strategies.Semantic proximity Read ↗

Clinical genome sequencing in neurodegenerative diseases-outcome in the first 500 patients.Semantic proximity Read ↗

Genetic Testing and Counseling in the Diagnosis and Management of Young-Onset DementiasSemantic proximity Read ↗

Genetic testing in dementia‐A medical genetics perspectiveSemantic proximity Read ↗

Validation of next-generation sequencing technologies in genetic diagnosis of dementia.Semantic proximity Read ↗

Genome sequencing for early-onset dementia: high diagnostic yield and frequent observation of multiple contributory allelesSemantic proximity Read ↗

Clinical exome sequencing in dementias: a preliminary study.Semantic proximity Read ↗

Alzheimer's Disease and Frontotemporal Dementia: The Current State of Genetics and Genetic Testing Since the Advent of Next-Generation Sequencing.Semantic proximity Read ↗

Genome sequencing for early-onset or atypical dementia: high diagnostic yield and frequent observation of multiple contributory alleles.Semantic proximity Read ↗

Genetics of dementia: update and guidelines for the clinician.Semantic proximity Read ↗

Predictors for a dementia gene mutation based on gene-panel next-generation sequencing of a large dementia referral series.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.