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Burkholderia cenocepacia ST-250 in cystic fibrosis patients in Switzerland: Genomic investigation of transmission routes.

Diagnostic microbiology and infectious disease - 1 Oct 2024

Zbinden Andrea, Seth-Smith Helena M B, Beltrami Vanessa, Mancini Stefano, Droz Sara, Bürgi Urs, Melillo David, Schuurmans Mace M, Schwizer Bernhard, Schmid Iris, Casaulta Carmen, Barben Jürg, Mueller Nicolas J, Imkamp Frank

Abstract excerpt

This report describes the characterization of Burkholderia cenocepacia isolates belonging to sequence type (ST)-250, detected in eight patients with cystic fibrosis (CF) in Switzerland. We retrospectively analyzed 18 isolates of B. cenocepacia ST-250 isolated between 2003 and 2015 by whole-genome sequencing and evaluated clinical and epidemiological data. Single nucleotide polymorphism analysis of the...

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PMID: 39116652
DOI: 10.1016/j.diagmicrobio.2024.116429

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