Article
Insights into the genome diversity and virulence of two clinical isolates of Burkholderia cenocepacia.
Journal of medical microbiology - 1 Aug 2018
Salloum Tamara, Nassour Elie, Araj George F, Abboud Edmond, Tokajian Sima
Abstract excerpt
PURPOSE: Burkholderia cenocepacia is among the most common members of the Burkholderia cepacia complex (Bcc) isolated from patients with cystic fibrosis (CF). The factors triggering the high rates of morbidity and mortality in CF patients are not well elucidated. In this study, we aim to highlight the genome diversity of two clinical isolates of B. cenocepacia through comparative genome analysis. METHODOLOGY: The...
Topics
- Adult
- Anti-Infective Agents
- Bacteriophages
- Burkholderia Infections
- Burkholderia cenocepacia
- Cystic Fibrosis
- DNA Transposable Elements
- Drug Resistance, Bacterial
- Genetic Variation
- Genome, Bacterial
- Humans
- Molecular Sequence Annotation
- Phylogeny
- Polymorphism, Single Nucleotide
- Virulence
- Virulence Factors