Article
The epigenetic determinants for systemic juvenile idiopathic arthritis phenotyping and treatment response.
BMC musculoskeletal disorders - 6 Aug 2024
Mosa Doaa Mosad, Mohsen Shorouk, Taman Mohamed, Khaled Nada, Gaafar Sherine Mohamed, Abdelhafez Mona S, Elmowafy Rasha, Elnagdy Marwa H, Sobh Ali
Abstract excerpt
BACKGROUND: Determining the role of epigenetics in systemic juvenile idiopathic arthritis (SJIA) provides an opportunity to explore previously unrecognized disease pathways and new therapeutic targets. AIM: We aimed to identify the clinical significance of microRNAs (miRNA-26a, miRNA-223) in SJIA. MATERIALS AND METHODS: This cross-sectional study was conducted on a group of children with SJIA attending to...
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