[Serrated dysplasia of the gastric fundus with malignant transformation: report of a case].

Abstract excerpt

报道1例胃底锯齿状异型增生伴癌变病例。患者胃底隆起型病变，镜下观察见肿瘤上皮显著的锯齿状改变，表面部分呈乳头状生长，腺体结构复杂，见低级别、高级别异型增生2种形态。免疫组织化学：MUC5AC阳性，MUC6部分阳性，p53异常过表达，Ki-67表达不定，热点区阳性指数60%。分子病理：KRAS基因第2号外显子突变。胃锯齿状异型增生临床较罕见，胃镜及病理医师易漏诊、低诊断，诊断主要依赖于病理学，且常与腺癌相伴，日常工作中应高度重视。.

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adenocarcinoma
• Share to Cell Transformation, Neoplastic
• Share to Gastric Mucosa