Article
Recommendations for Surveillance for Children with Leukemia-Predisposing Conditions.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Jun 2017
Porter Christopher C, Druley Todd E, Erez Ayelet, Kuiper Roland P, Onel Kenan, Schiffman Joshua D, Wolfe Schneider Kami, Scollon Sarah R, Scott Hamish S, Strong Louise C, Walsh Michael F, Nichols Kim E
Abstract excerpt
Leukemia, the most common childhood cancer, has long been recognized to occasionally run in families. The first clues about the genetic mechanisms underlying familial leukemia emerged in 1990 when Li-Fraumeni syndrome was linked to TP53 mutations. Since this discovery, many other genes associated with hereditary predisposition to leukemia have been identified. Although several of these disorders also predispose...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.