Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Discovery of the Natural Bibenzyl Compound Erianin in Dendrobium Inhibiting the Growth and EMT of Gastric Cancer through Downregulating the LKB1-SIK2/3-PARD3 Pathway

21 Jul 2024

Abstract excerpt

is a tumor-suppressor gene, and its mutation is an important driver of various cancers. Yet some studies have reported contradictory findings. In this study, we combined bioinformatics and in vitro and in vivo experiments to investigate the effect and potential mechanism of Erianin in the treatment of GC. The results show that LKB1 was highly expressed in patients' tumor tissues and GC cells, and it was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological and pharmacological studies of plants
Share to Cancer-related molecular mechanisms research
Share to Plant Molecular Biology Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39063214
DOI: 10.3390/ijms25147973

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Discovery of the Natural Bibenzyl Compound Erianin in Dendrobium Inhibiting the Growth and EMT of Gastric Cancer through Downregulating the LKB1-SIK2/3-PARD3 PathwayPMID 39063214Read ↗

A novel multi-scale bioinformatics strategy for identifying the molecular mechanism by insighting into ceRNA network integrating WGCNA and meta-analysis: compound kushen injection for treating gastric carcinoma as a proofSemantic proximity Read ↗

Morin Modulates Key Targets and Pathways Associated with Gastric Cancer: Network Pharmacology, Molecular Docking, Molecular Dynamics, ADMET, and In‑Vitro AnalysisSemantic proximity Read ↗

α-Tomatine Inhibits Proliferation, Metastasis, Drug Resistance and Immune Infiltration Through the PI3K-AKT-MAPK Axis in Gastric CancerSemantic proximity Read ↗

A Network Pharmacology Approach for Uncovering the Antitumor Effects and Potential Mechanisms of the Sijunzi Decoction for the Treatment of Gastric CancerSemantic proximity Read ↗

Apigenin role as cell-signaling pathways modulator: implications in cancer prevention and treatmentSemantic proximity Read ↗

Nitidine chloride inhibits proliferation and induces apoptosis in colorectal cancer cells by activating the p53 signaling pathwaySemantic proximity Read ↗

Integrated analysis of Dendrobium nobile extract Dendrobin A against pancreatic ductal adenocarcinoma based on network pharmacology, bioinformatics, and validation experimentsSemantic proximity Read ↗

Silencing GDI2 inhibits proliferation, migration and invasion of colorectal cancer through activation of p53 signaling pathwaySemantic proximity Read ↗

Erianin facilitates pyroptosis in endometrial cancer via targeting m6A reader YTHDF1Semantic proximity Read ↗

Genistein exerts anti-colorectal cancer actions: clinical reports, computational and validated findingsSemantic proximity Read ↗

Andrographis overcomes 5-fluorouracil-associated chemoresistance through inhibition of DKK1 in colorectal cancerSemantic proximity Read ↗

FOXO3a‐dependent Parkin regulates the development of gastric cancer by targeting ATP‐binding cassette transporter E1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.