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Article

Perinatal nicotine vaping exposure induces pro-myofibroblastic phenotype in rat bone marrow-derived mesenchymal stem cells.

Reproductive toxicology (Elmsford, N.Y.) - 1 Oct 2024

Yu Celia, Liu Jie, Sakurai Reiko, Wang Ying, Afrose Leela, Gour Abhishek, Sharma Abhisheak, Chandan Gourav, Rehan Virender K

Abstract excerpt

Perinatal nicotine exposure via tobacco smoking results in increased proclivity to chronic lung disease (CLD); however, the underlying molecular mechanisms remain incompletely understood. We previously demonstrated that in addition to nicotine's direct effects on the developing lung, there are also adverse molecular alterations in bone marrow-derived mesenchymal stem cells (BMSCs), which are vital to lung injury...

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Bone Marrow Cells
Mesenchymal Stem Cells
Myofibroblasts
Nicotine
Nicotinic Agonists

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Prenatal Exposure Delayed Effects

Rats, Sprague-Dawley

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Open in PubMed Open full text

Identifiers

PMID: 39059775
DOI: 10.1016/j.reprotox.2024.108673
PMCID: PMC11377149

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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