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Article

Charting the Impact of Maternal Antibodies and Repeat Exposures on Sapovirus Immunity in Early Childhood From a Nicaraguan Birth Cohort.

The Journal of infectious diseases - 20 Feb 2025

Bucardo Filemón, Mallory Michael L, González Fredman, Reyes Yaoska, Vielot Nadja A, Yount Boyd L, Sims Amy C, Nguyen Cameron, Cross Kaitlyn, Toval-Ruíz Christian, Gutiérrez Lester, Vinjé Jan, Baric Ralph S, Lindesmith Lisa C, Becker-Dreps Sylvia

Abstract excerpt

BACKGROUND: Sapovirus is an important cause of acute gastroenteritis in childhood. While vaccines against sapovirus may reduce gastroenteritis burden, a major challenge to their development is a lack of information about natural immunity. METHODS: We measured sapovirus-specific IgG in serum collected between 2017 and 2020 of mothers soon after delivery and at 6 time points in Nicaraguan children until 3 years of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39042731
DOI: 10.1093/infdis/jiae368
PMCID: PMC11841625

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