Reported Adverse Events in a Multicenter Cohort of Patients Ages 6-18 Years with Cystic Fibrosis and at Least One F508del Allele Receiving Elexacaftor/Tezacaftor/Ivacaftor.

doi:10.1016/j.jpeds.2024.114176

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Reported Adverse Events in a Multicenter Cohort of Patients Ages 6-18 Years with Cystic Fibrosis and at Least One F508del Allele Receiving Elexacaftor/Tezacaftor/Ivacaftor.

The Journal of pediatrics - 1 Nov 2024

Terlizzi Vito, Fevola Cristina, Presti Santiago, Castaldo Alice, Daccò Valeria, Claut Laura, Sepe Angela, Majo Fabio, Casciaro Rosaria, Esposito Irene, Vitullo Pamela, Salvi Marta, Troiani Patrizia, Ficili Francesca, Parisi Giuseppe Fabio, Pantano Stefano, Costa Stefano, Leonetti Giuseppina, Palladino Nicola, Taccetti Giovanni, Bonomi Paolo, Salvatore Donatello

Abstract excerpt

OBJECTIVE: The objective of this study was to describe reported adverse events (AEs) associated with elexacaftor/tezacaftor/ivacaftor (ETI) in a pediatric sample with cystic fibrosis (CF) aged 6-18 years, with at least one F508del variant, followed at multiple Italian CF centers. STUDY DESIGN: This was a retrospective, multicenter, observational study. All children receiving ETI therapy from October 2019 to...

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PMID: 38945446
DOI: 10.1016/j.jpeds.2024.114176

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