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Article

Impact of chronic medication de-escalation in patients with cystic fibrosis taking elexacaftor, tezacaftor, ivacaftor: A retrospective review.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Jan 2024

Guenther Emma L, McCoy Karen S, Eisner Mariah, Bai Shasha, Nemastil Christopher J, Novak Kimberly J, Johnson Terri, Stephan Emily M

Abstract excerpt

BACKGROUND: This single-center, retrospective study evaluated the effects of de-escalating cystic fibrosis (CF) supportive therapies in patients on elexacaftor/tezacaftor/ivacaftor (ETI). For many with CF, the clinical benefit of ETI exceeds that of supportive therapies. Therefore, we anticipated patients would desire to discontinue many of their supportive therapies, leading to the creation of a de-escalation...

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Identifiers

PMID: 37069044
DOI: 10.1016/j.jcf.2023.03.018

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