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Environmental Hot Spots and Resistance-Associated Application Practices for Azole-Resistant Aspergillus fumigatus, Denmark, 2020-2023.

Emerging infectious diseases - 1 Aug 2024

Arendrup Maiken Cavling, Hare Rasmus Krøger, Jørgensen Karin Meinike, Bollmann Ulla E, Bech Tina B, Hansen Cecilie Cetti, Heick Thies M, Jørgensen Lise Nistrup

Abstract excerpt

Azole-resistant Aspergillus fumigatus (ARAf) fungi have been found inconsistently in the environment in Denmark since 2010. During 2018-2020, nationwide surveillance of clinical A. fumigatus fungi reported environmental TR34/L98H or TR46/Y121F/T289A resistance mutations in 3.6% of isolates, prompting environmental sampling for ARAf and azole fungicides and investigation for selection of ARAf in field and...

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Identifiers

PMID: 38935978
DOI: 10.3201/eid3008.240096
PMCID: PMC11286046

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