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Article

Hydropathic AF-2 variants in the androgen receptor gene among androgen insensitivity patients.

Andrology - 1 Mar 2025

Giuliatti Silvana, Benedetti Anna Flavia Figueredo, Ramos Raquel Martinez, Petroli Reginaldo José, Domenice Sorahia, Mendonca Berenice Bilharinho, Batista Rafael Loch

Abstract excerpt

BACKGROUND: Androgen insensitivity syndrome (AIS) is a common condition among individuals with differences of sexual development (DSD) and results from germline allelic variants in the androgen receptor (AR) gene. Understanding the phenotypic consequences of AR allelic variants that disrupt the activation function 2 (AF2) region is essential to grasping its clinical significance. OBJECTIVES: This study aims to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 38923406
DOI: 10.1111/andr.13680

Genes

AR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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