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Elucidating sleep disorders: a comprehensive bioinformatics analysis of functional gene sets and hub genes

11 Jun 2024

Abstract excerpt

Background: Sleep disorders (SD) are known to have a profound impact on human health and quality of life although their exact pathogenic mechanisms remain poorly understood. Methods: The study first accessed SD datasets from the GEO and identified DEGs. These DEGs were then subjected to gene set enrichment analysis. Several advanced techniques, including the RF, SVM-RFE, PPI networks, and LASSO methodologies,...

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PMID: 38919616
DOI: 10.3389/fimmu.2024.1381765

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