Article
Assessment of interleukin-18 gene polymorphism and serum levels in cutaneous lichen planus.
European journal of medical research - 26 Jun 2024
Doss Reham William, El-Rifaie Abdel-Aziz, Roshdy Anton Nasr, Sabry Dina
Abstract excerpt
BACKGROUND: Lichen planus (LP) is a chronic inflammatory disease with uncertain etiology. Interleukin-18 (IL-18) is an interferon gamma (INFγ) inducing agent. It is a pro-inflammatory cytokine that was found to play a role in the pathogenesis of some autoimmune disorders. MATERIAL AND METHODS: This study included 50 patients with classic cutaneous lichen planus (CLP) and 50 healthy volunteers serving as controls....
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