Article
Comparative effectiveness of lazertinib in patients with EGFR T790M-positive non-small-cell lung cancer using a real-world external control.
Scientific reports - 25 Jun 2024
Jeon Ha-Lim, Kwak Meesong, Kim Sohee, Yu Hye-Yeon, Shin Ju-Young, Jung Hyun Ae
Abstract excerpt
Lazertinib is a recently developed third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors used for patients with advanced EGFR T790M-positive non-small-cell lung cancer. We evaluated the effectiveness of lazertinib compared with osimertinib using an external control. We obtained individual patient data for the lazertinib arm from the LASER201 trial and the osimertinib arm from...
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