Article
Outcomes of acute myeloid leukemia patients who responded to venetoclax and azacitidine and stopped treatment.
American journal of hematology - 1 Oct 2024
Garciaz Sylvain, Dumas Pierre-Yves, Bertoli Sarah, Sallman David A, Decroocq Justine, Belhabri Amine, Orvain Corentin, Aspas Requena Gaspar, Simand Celestine, Laribi Kamel, Carré Martin, Santagostino Alberto, Himberlin Chantal, Peterlin Pierre, Bonnet Sarah, Chan Onyee, Lancet Jeffrey, Komrokji Rami, Vergez François, Chapuis Nicolas, Raskovalova Tatiana, Plesa Adriana, Lhoumeau Anne-Catherine, Mineur Ariane, Hospital Marie Anne, Pigneux Arnaud, Vey Norbert, Récher Christian
Abstract excerpt
Venetoclax-azacitidine is the standard of treatment for unfit acute myeloid leukemia patients. In the VIALE-A study, treatment was given until progression but there are no data on its optimal duration for responding patients who do not tolerate indefinite therapy. We retrospectively analyzed the outcome of patients who discontinued venetoclax or venetoclax-azacitidine due to poor tolerance. Sixty-two newly...
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