Tetrahedral framework nucleic acids‐based delivery of microRNA ‐155 alleviates intervertebral disc degeneration through targeting Bcl‐2/Bax apoptosis pathway

Abstract excerpt

Intervertebral disc degeneration (IDD) is one of the most common causes of chronic low back pain, which does great harm to patients' life quality. At present, the existing treatment options are mostly aimed at relieving symptoms, but the long-term efficacy is not ideal. Tetrahedral framework nucleic acids (tFNAs) are regarded as a type of nanomaterial with excellent biosafety and prominent performance in...

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