Article
Deep sequencing of Escherichia coli exposes colonisation diversity and impact of antibiotics in Punjab, Pakistan.
Nature communications - 18 Jun 2024
Khawaja Tamim, Mäklin Tommi, Kallonen Teemu, Gladstone Rebecca A, Pöntinen Anna K, Mero Sointu, Thorpe Harry A, Samuelsen Ørjan, Parkhill Julian, Izhar Mateen, Akhtar M Waheed, Corander Jukka, Kantele Anu
Abstract excerpt
Multi-drug resistant (MDR) E. coli constitute a major public health burden globally, reaching the highest prevalence in the global south yet frequently flowing with travellers to other regions. However, our comprehension of the entire genetic diversity of E. coli colonising local populations remains limited. We quantified this diversity, its associated antimicrobial resistance (AMR), and assessed the impact of...
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