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Gut microbiota dysbiosis-related susceptibility to nontuberculous mycobacterial lung disease

11 Jun 2024

Abstract excerpt

The role of gut microbiota in host defense against nontuberculous mycobacterial lung disease (NTM-LD) was poorly understood. Here, we showed significant gut microbiota dysbiosis in patients with NTM-LD. Reduced abundance of Prevotella copri was significantly associated with NTM-LD and its disease severity. Compromised TLR2 activation activity in feces and plasma in the NTM-LD patients was highlighted. In the...

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PMID: 38860456
DOI: 10.1080/19490976.2024.2361490

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