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Article

Symptom phenotyping in people with cystic fibrosis during acute pulmonary exacerbations using machine-learning K-means clustering analysis.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Nov 2024

Gill Eliana R, Dill Christopher, Goss Christopher H, Sagel Scott D, Wright Michelle L, Horner Sharon D, Zuñiga Julie A

Abstract excerpt

INTRODUCTION: People with cystic fibrosis (PwCF) experience frequent symptoms associated with chronic lung disease. A complication of CF is a pulmonary exacerbation (PEx), which is often preceded by an increase in symptoms and a decline in lung function. A symptom cluster is when two or more symptoms co-occur and are related; symptom clusters have contributed meaningful knowledge in other diseases. The purpose of...

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Identifiers

PMID: 38851922
DOI: 10.1016/j.jcf.2024.05.014
PMCID: PMC11624099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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