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Article

Pharmacological targets of SGLT2 inhibitors on IgA nephropathy and membranous nephropathy: a mendelian randomization study

22 May 2024

Abstract excerpt

Introduction: Emerging research suggests that sodium-glucose cotransporter 2 (SGLT2) inhibitors may play a pivotal role in the treatment of primary glomerular diseases. This study was aimed to investigate potential pharmacological targets connecting SGLT2 inhibitors with IgA nephropathy (IgAN) and membranous nephropathy (MN). Methods: A univariate Mendelian randomization (MR) analysis was conducted using publicly...

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Share to Chronic Kidney Disease and Diabetes
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38846092
DOI: 10.3389/fphar.2024.1399881

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