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Using expression data to fine map QTL associated with fertility in dairy cattle.

Genetics, selection, evolution : GSE - 6 Jun 2024

van den Berg Irene, Chamberlain Amanda J, MacLeod Iona M, Nguyen Tuan V, Goddard Mike E, Xiang Ruidong, Mason Brett, Meier Susanne, Phyn Claire V C, Burke Chris R, Pryce Jennie E

Abstract excerpt

BACKGROUND: Female fertility is an important trait in dairy cattle. Identifying putative causal variants associated with fertility may help to improve the accuracy of genomic prediction of fertility. Combining expression data (eQTL) of genes, exons, gene splicing and allele specific expression is a promising approach to fine map QTL to get closer to the causal mutations. Another approach is to identify genomic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38844868
DOI: 10.1186/s12711-024-00912-8
PMCID: PMC11154999

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